Mike Schaekermann, Research Lead, Google Research, and Alan Karthikesalingam, Director/Principal Scientist, Google DeepMind We present insights from a first-of-its-kind research study in partnership with Beth Israel Deaconess Medical Center towards prospective real-world assessment of AMIE, our conversational medical AI for clinical reasoning and dialogue. Quick links Paper Share Copy link × AI systems capable of clinical reasoning and dialogue have the potential to dramatically increase access to medical expertise and care while giving physicians back time with their patients. Yet, bringing these innovations to life demands a safety-centric, evidence-based approach. In recent years, our work with the Articulate Medical Intelligence Explorer (AMIE) has explored the possibilities of conversational medical AI, starting with demonstrations of its diagnostic capabilities in simulated settings when assisting clinicians in diagnostic challenges and interacting with patient actors . …