Amazon Bedrock introduces two paths to enforce single-Region data residency for Claude Code: Path 1 uses the Mantle endpoint with native single-Region routing in seven Regions (Ireland, Stockholm, Tokyo, Melbourne, US East (N. Virginia), US East (Ohio), US West (Oregon)), and Path 2 uses the classic Invoke API with an application inference profile, currently only supported in London (eu-west-2) for Claude Opus 4.6 and Sonnet 4.6.
From the source
we show you both paths, why the choice depends on your Region, the AWS Identity and Access Management (IAM) policy that enforces them, and how to verify compliance in AWS CloudTrail.
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