Anthropic announces updates to Claude Fable 5's biology safeguards that reduce false positives, cutting biology-related fallbacks by about 85%. This allows Fable 5 to assist with a wider range of biology tasks, including everyday health and educational questions, while still falling back to Opus 5 for dual-use requests.
From the source
In our testing, this update reduced biology-related fallbacks by about 85% across our product surfaces.
anthropic.com